Highly accurate diagnosis of cancer in thyroid nodules with follicular neoplasm/suspicious for a follicular neoplasm cytology by ThyroSeq v2 next-generation sequencing assay.
Identifieur interne : 002A22 ( Main/Exploration ); précédent : 002A21; suivant : 002A23Highly accurate diagnosis of cancer in thyroid nodules with follicular neoplasm/suspicious for a follicular neoplasm cytology by ThyroSeq v2 next-generation sequencing assay.
Auteurs : Yuri E. Nikiforov [États-Unis] ; Sally E. Carty ; Simon I. Chiosea ; Christopher Coyne ; Umamaheswar Duvvuri ; Robert L. Ferris ; William E. Gooding ; Steven P. Hodak ; Shane O. Lebeau ; N Paul Ohori ; Raja R. Seethala ; Mitchell E. Tublin ; Linwah Yip ; Marina N. NikiforovaSource :
- Cancer [ 1097-0142 ] ; 2014.
Descripteurs français
- KwdFr :
- Adénocarcinome folliculaire (anatomopathologie), Adénocarcinome folliculaire (diagnostic), Adénocarcinome folliculaire (génétique), Adénome oxyphile, Adénomes (anatomopathologie), Adénomes (diagnostic), Adénomes (génétique), Analyse de séquence d'ADN, Carcinomes (anatomopathologie), Carcinomes (diagnostic), Carcinomes (génétique), Cytoponction, Fusion de gènes (génétique), Humains, Mutation, Nodule thyroïdien (anatomopathologie), Nodule thyroïdien (diagnostic), Nodule thyroïdien (génétique), Techniques de diagnostic moléculaire, Tumeurs de la thyroïde (anatomopathologie), Tumeurs de la thyroïde (diagnostic), Tumeurs de la thyroïde (génétique), Études de cohortes, Études prospectives, Études rétrospectives.
- MESH :
- anatomopathologie : Adénocarcinome folliculaire, Adénomes, Carcinomes, Nodule thyroïdien, Tumeurs de la thyroïde.
- diagnostic : Adénocarcinome folliculaire, Adénomes, Carcinomes, Nodule thyroïdien, Tumeurs de la thyroïde.
- génétique : Adénocarcinome folliculaire, Adénomes, Carcinomes, Fusion de gènes, Nodule thyroïdien, Tumeurs de la thyroïde.
- Adénome oxyphile, Analyse de séquence d'ADN, Cytoponction, Humains, Mutation, Techniques de diagnostic moléculaire, Études de cohortes, Études prospectives, Études rétrospectives.
English descriptors
- KwdEn :
- Adenocarcinoma, Follicular (diagnosis), Adenocarcinoma, Follicular (genetics), Adenocarcinoma, Follicular (pathology), Adenoma (diagnosis), Adenoma (genetics), Adenoma (pathology), Adenoma, Oxyphilic, Biopsy, Fine-Needle, Carcinoma (diagnosis), Carcinoma (genetics), Carcinoma (pathology), Cohort Studies, Gene Fusion (genetics), Humans, Molecular Diagnostic Techniques, Mutation, Prospective Studies, Retrospective Studies, Sequence Analysis, DNA, Thyroid Neoplasms (diagnosis), Thyroid Neoplasms (genetics), Thyroid Neoplasms (pathology), Thyroid Nodule (diagnosis), Thyroid Nodule (genetics), Thyroid Nodule (pathology).
- MESH :
- diagnosis : Adenocarcinoma, Follicular, Adenoma, Carcinoma, Thyroid Neoplasms, Thyroid Nodule.
- genetics : Adenocarcinoma, Follicular, Adenoma, Carcinoma, Gene Fusion, Thyroid Neoplasms, Thyroid Nodule.
- pathology : Adenocarcinoma, Follicular, Adenoma, Carcinoma, Thyroid Neoplasms, Thyroid Nodule.
- Adenoma, Oxyphilic, Biopsy, Fine-Needle, Cohort Studies, Humans, Molecular Diagnostic Techniques, Mutation, Prospective Studies, Retrospective Studies, Sequence Analysis, DNA.
Abstract
Fine-needle aspiration (FNA) cytology is a common approach to evaluating thyroid nodules, although 20% to 30% of FNAs have indeterminate cytology, which hampers the appropriate management of these patients. Follicular (or oncocytic) neoplasm/suspicious for a follicular (or oncocytic) neoplasm (FN/SFN) is a common indeterminate diagnosis with a cancer risk of approximately 15% to 30%. In this study, the authors tested whether the most complete next-generation sequencing (NGS) panel of genetic markers could significantly improve cancer diagnosis in these nodules.
DOI: 10.1002/cncr.29038
PubMed: 25209362
Affiliations:
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Chiosea</name></author><author><name sortKey="Coyne, Christopher" sort="Coyne, Christopher" uniqKey="Coyne C" first="Christopher" last="Coyne">Christopher Coyne</name></author><author><name sortKey="Duvvuri, Umamaheswar" sort="Duvvuri, Umamaheswar" uniqKey="Duvvuri U" first="Umamaheswar" last="Duvvuri">Umamaheswar Duvvuri</name></author><author><name sortKey="Ferris, Robert L" sort="Ferris, Robert L" uniqKey="Ferris R" first="Robert L" last="Ferris">Robert L. Ferris</name></author><author><name sortKey="Gooding, William E" sort="Gooding, William E" uniqKey="Gooding W" first="William E" last="Gooding">William E. Gooding</name></author><author><name sortKey="Hodak, Steven P" sort="Hodak, Steven P" uniqKey="Hodak S" first="Steven P" last="Hodak">Steven P. Hodak</name></author><author><name sortKey="Lebeau, Shane O" sort="Lebeau, Shane O" uniqKey="Lebeau S" first="Shane O" last="Lebeau">Shane O. 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Nikiforova</name></author></analytic><series><title level="j">Cancer</title><idno type="eISSN">1097-0142</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adenocarcinoma, Follicular (diagnosis)</term><term>Adenocarcinoma, Follicular (genetics)</term><term>Adenocarcinoma, Follicular (pathology)</term><term>Adenoma (diagnosis)</term><term>Adenoma (genetics)</term><term>Adenoma (pathology)</term><term>Adenoma, Oxyphilic</term><term>Biopsy, Fine-Needle</term><term>Carcinoma (diagnosis)</term><term>Carcinoma (genetics)</term><term>Carcinoma (pathology)</term><term>Cohort Studies</term><term>Gene Fusion (genetics)</term><term>Humans</term><term>Molecular Diagnostic Techniques</term><term>Mutation</term><term>Prospective Studies</term><term>Retrospective Studies</term><term>Sequence Analysis, DNA</term><term>Thyroid Neoplasms (diagnosis)</term><term>Thyroid Neoplasms (genetics)</term><term>Thyroid Neoplasms (pathology)</term><term>Thyroid Nodule (diagnosis)</term><term>Thyroid Nodule (genetics)</term><term>Thyroid Nodule (pathology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adénocarcinome folliculaire (anatomopathologie)</term><term>Adénocarcinome folliculaire (diagnostic)</term><term>Adénocarcinome folliculaire (génétique)</term><term>Adénome oxyphile</term><term>Adénomes (anatomopathologie)</term><term>Adénomes (diagnostic)</term><term>Adénomes (génétique)</term><term>Analyse de séquence d'ADN</term><term>Carcinomes (anatomopathologie)</term><term>Carcinomes (diagnostic)</term><term>Carcinomes (génétique)</term><term>Cytoponction</term><term>Fusion de gènes (génétique)</term><term>Humains</term><term>Mutation</term><term>Nodule thyroïdien (anatomopathologie)</term><term>Nodule thyroïdien (diagnostic)</term><term>Nodule thyroïdien (génétique)</term><term>Techniques de diagnostic moléculaire</term><term>Tumeurs de la thyroïde (anatomopathologie)</term><term>Tumeurs de la thyroïde (diagnostic)</term><term>Tumeurs de la thyroïde (génétique)</term><term>Études de cohortes</term><term>Études prospectives</term><term>Études rétrospectives</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Adénocarcinome folliculaire</term><term>Adénomes</term><term>Carcinomes</term><term>Nodule thyroïdien</term><term>Tumeurs de la thyroïde</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Adenocarcinoma, Follicular</term><term>Adenoma</term><term>Carcinoma</term><term>Thyroid Neoplasms</term><term>Thyroid Nodule</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Adénocarcinome folliculaire</term><term>Adénomes</term><term>Carcinomes</term><term>Nodule thyroïdien</term><term>Tumeurs de la thyroïde</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Adenocarcinoma, Follicular</term><term>Adenoma</term><term>Carcinoma</term><term>Gene Fusion</term><term>Thyroid Neoplasms</term><term>Thyroid Nodule</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Adénocarcinome folliculaire</term><term>Adénomes</term><term>Carcinomes</term><term>Fusion de gènes</term><term>Nodule thyroïdien</term><term>Tumeurs de la thyroïde</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Adenocarcinoma, Follicular</term><term>Adenoma</term><term>Carcinoma</term><term>Thyroid Neoplasms</term><term>Thyroid Nodule</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adenoma, Oxyphilic</term><term>Biopsy, Fine-Needle</term><term>Cohort Studies</term><term>Humans</term><term>Molecular Diagnostic Techniques</term><term>Mutation</term><term>Prospective Studies</term><term>Retrospective Studies</term><term>Sequence Analysis, DNA</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adénome oxyphile</term><term>Analyse de séquence d'ADN</term><term>Cytoponction</term><term>Humains</term><term>Mutation</term><term>Techniques de diagnostic moléculaire</term><term>Études de cohortes</term><term>Études prospectives</term><term>Études rétrospectives</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Fine-needle aspiration (FNA) cytology is a common approach to evaluating thyroid nodules, although 20% to 30% of FNAs have indeterminate cytology, which hampers the appropriate management of these patients. Follicular (or oncocytic) neoplasm/suspicious for a follicular (or oncocytic) neoplasm (FN/SFN) is a common indeterminate diagnosis with a cancer risk of approximately 15% to 30%. In this study, the authors tested whether the most complete next-generation sequencing (NGS) panel of genetic markers could significantly improve cancer diagnosis in these nodules.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Pennsylvanie</li></region></list><tree><noCountry><name sortKey="Carty, Sally E" sort="Carty, Sally E" uniqKey="Carty S" first="Sally E" last="Carty">Sally E. Carty</name><name sortKey="Chiosea, Simon I" sort="Chiosea, Simon I" uniqKey="Chiosea S" first="Simon I" last="Chiosea">Simon I. Chiosea</name><name sortKey="Coyne, Christopher" sort="Coyne, Christopher" uniqKey="Coyne C" first="Christopher" last="Coyne">Christopher Coyne</name><name sortKey="Duvvuri, Umamaheswar" sort="Duvvuri, Umamaheswar" uniqKey="Duvvuri U" first="Umamaheswar" last="Duvvuri">Umamaheswar Duvvuri</name><name sortKey="Ferris, Robert L" sort="Ferris, Robert L" uniqKey="Ferris R" first="Robert L" last="Ferris">Robert L. Ferris</name><name sortKey="Gooding, William E" sort="Gooding, William E" uniqKey="Gooding W" first="William E" last="Gooding">William E. Gooding</name><name sortKey="Hodak, Steven P" sort="Hodak, Steven P" uniqKey="Hodak S" first="Steven P" last="Hodak">Steven P. Hodak</name><name sortKey="Lebeau, Shane O" sort="Lebeau, Shane O" uniqKey="Lebeau S" first="Shane O" last="Lebeau">Shane O. Lebeau</name><name sortKey="Nikiforova, Marina N" sort="Nikiforova, Marina N" uniqKey="Nikiforova M" first="Marina N" last="Nikiforova">Marina N. Nikiforova</name><name sortKey="Ohori, N Paul" sort="Ohori, N Paul" uniqKey="Ohori N" first="N Paul" last="Ohori">N Paul Ohori</name><name sortKey="Seethala, Raja R" sort="Seethala, Raja R" uniqKey="Seethala R" first="Raja R" last="Seethala">Raja R. Seethala</name><name sortKey="Tublin, Mitchell E" sort="Tublin, Mitchell E" uniqKey="Tublin M" first="Mitchell E" last="Tublin">Mitchell E. Tublin</name><name sortKey="Yip, Linwah" sort="Yip, Linwah" uniqKey="Yip L" first="Linwah" last="Yip">Linwah Yip</name></noCountry><country name="États-Unis"><region name="Pennsylvanie"><name sortKey="Nikiforov, Yuri E" sort="Nikiforov, Yuri E" uniqKey="Nikiforov Y" first="Yuri E" last="Nikiforov">Yuri E. Nikiforov</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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